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Radiotherapy

General & Planning

External Beam RadiotherapyImage-Guided RadiotherapyIMRT and VMATRadiotherapyRadiotherapy Planning and Simulation

During Treatment

Daily Life During RadiotherapyRadiotherapy Side Effects

Focused Treatments

BrachytherapyGamma KnifeMR-LINACProton TherapySRS and SBRT

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Radiotherapy for Pain Relief
FAQsRadiotherapy
All Radiotherapy guides19

General & Planning

External Beam RadiotherapyImage-Guided RadiotherapyIMRT and VMATRadiotherapyRadiotherapy Planning and Simulation

During Treatment

Daily Life During RadiotherapyRadiotherapy Side Effects

Focused Treatments

BrachytherapyGamma KnifeMR-LINACProton TherapySRS and SBRT

Cancer Types

Brain Tumour RadiotherapyBreast Cancer RadiotherapyCervical Cancer RadiotherapyHead and Neck Cancer RadiotherapyLung Cancer RadiotherapyProstate Cancer Radiotherapy

Symptom Relief

Radiotherapy for Pain Relief

Gamma Knife

2 min read
Written by Taiwo Oluwayemisi, B.Sc Radiography
·
Medically reviewed by Olusegun Samuel Faith, M.Sc (Medical Imaging), MPH, PgDip (MRI)
Education only — not medical advice. For urgent symptoms, see a doctor.

RadFAQS explains radiology terms, scan preparation, and what patients commonly experience. It is not a diagnosis, treatment plan, or replacement for your referring doctor, radiologist, or care team. RadFAQS does not monitor this site for emergencies and cannot respond in real time. If symptoms are severe, worsening, or urgent, do not wait for a reply here — contact a healthcare professional or emergency service immediately.

Table of Contents

Common Indications for Gamma KnifeWhat exactly does Gamma Knife treat?Is it brain surgery?How should I prepare?What happens when I arrive?How is the treatment performed?How long does Gamma Knife take?Is there any discomfort?Are there risks?Will the tumour disappear immediately?Can I have Gamma Knife if I am pregnant?Conclusion

Gamma Knife is a type of stereotactic radiosurgery used to treat selected problems in the brain. It uses many small radiation beams that meet at a carefully planned target.

Despite the name, there is no knife and no surgical cut. The treatment is called radiosurgery because it treats a small target very precisely.

Common Indications for Gamma Knife

Your doctor may consider Gamma Knife for:

  • Small brain metastases.
  • Some benign brain tumours.
  • Acoustic neuroma or vestibular schwannoma.
  • Meningioma in selected cases.
  • Arteriovenous malformation (AVM).
  • Trigeminal neuralgia in selected cases.
  • Small targets near sensitive brain structures.

What exactly does Gamma Knife treat?

It treats a small target inside the head. It is not used for cancers spread throughout the whole body.

Is it brain surgery?

No. There is no opening of the skull. Some systems use a head frame fixed to the skull with pins, while others use a mask. Your centre will explain which setup they use.

How should I prepare?

You may need MRI, CT, blood tests, and a planning review. Tell the team if you take blood thinners, have a pacemaker, have metal implants, or struggle with tight spaces.

What happens when I arrive?

The team confirms the target and prepares your head position. If a frame is used, local anaesthetic is given where the pins touch the scalp.

How is the treatment performed?

You lie on the treatment couch while the machine delivers focused radiation to the target. You do not feel the radiation.

How long does Gamma Knife take?

The actual treatment may take minutes to a few hours, depending on the number and size of targets. The full visit can take longer because of imaging, planning, frame placement, and recovery.

Is there any discomfort?

The radiation is painless. You may feel pressure from a head frame, discomfort from lying still, or anxiety from the setup.

Are there risks?

Risks depend on the target. They can include headache, nausea, scalp soreness, swelling around the treated area, seizures, or delayed radiation effects. Your team should explain warning symptoms before you leave.

Will the tumour disappear immediately?

Usually no. Gamma Knife often works slowly. Follow-up scans may show shrinkage, stability, or reduced activity over time.

Can I have Gamma Knife if I am pregnant?

Pregnancy Precaution

Tell your doctor if you are pregnant or think you might be. Gamma Knife uses radiation, so pregnancy must be discussed before treatment.

Conclusion

Gamma Knife can sound frightening because of the name, but it is a focused radiation treatment, not open brain surgery. Ask whether you will have a frame or mask, how long the day may take, and what symptoms should make you call after treatment.

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Related dictionary terms

Disease

Acoustic Neuroma

An acoustic neuroma, also called a vestibular schwannoma, is a tumor on the nerve involved in hearing and balance.

Disease

Meningioma

A meningioma is a tumor that arises from the coverings around the brain or spinal cord and is often benign, though not always harmless.

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Back to Radiotherapy guides

Table of Contents

Common Indications for Gamma KnifeWhat exactly does Gamma Knife treat?Is it brain surgery?How should I prepare?What happens when I arrive?How is the treatment performed?How long does Gamma Knife take?Is there any discomfort?Are there risks?Will the tumour disappear immediately?Can I have Gamma Knife if I am pregnant?Conclusion